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An expert panel hosted by
Customizing first-line BTK inhibitors for CLL
with Gilles Salles, Paolo Ghia, and Francesc Bosch
Wednesday, October 23, 2024
18:30-19:30 BST
This independent educational activity is supported by Pharmacyclics LLC, an AbbVie Company and Janssen Biotech. All content is developed independently by the faculty. The funder is allowed no influence on the content of this activity.
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On 9 February 2019, Azadeh Armaee from the Iran University of Medical Sciences, Tehran, IR, and colleagues, published in Clinical and Translational Oncology a meta-analysis of seven clinical trials in order to investigate the efficacy of nivolumab on classical Hodgkin lymphoma (cHL) patients.
In this meta-analysis (CRD42018105712), data from seven studies were pooled to assess cHL patient outcomes following treatment with the PD1 inhibitor, nivolumab. The primary aim of this analysis was to calculate the overall objective response rate and survival rate of cHL patients on nivolumab.
The results of this meta-analysis indicated that nivolumab, a PD-1 inhibitor, shows promising efficacy in relapsed or refractory cHL patients. Moreover, nivolumab-related AEs were manageable in most cases. The authors mentioned that among the limitations of this study is that fact that most evaluated studies were cohort trials with only a few having a control arm.
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