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An expert panel hosted by
Customizing first-line BTK inhibitors for CLL
with Gilles Salles, Paolo Ghia, and Francesc Bosch
Wednesday, October 23, 2024
18:30-19:30 BST
This independent educational activity is supported by Pharmacyclics LLC, an AbbVie Company and Janssen Biotech. All content is developed independently by the faculty. The funder is allowed no influence on the content of this activity.
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On October 15, 2020, the U.S. Food and Drug Administration (FDA) announced the approval of pembrolizumab as a monotherapy for the treatment of relapsed or refractory (R/R) classical Hodgkin lymphoma (cHL). The extended indication of pembrolizumab includes adult patients with R/R cHL following frontline therapy and pediatric patients with refractory cHL or relapsed disease following ≥ 2 lines of therapy.
The decision was based on the randomized phase III KEYNOTE-204 trial (NCT02684292), which resulted in the priority review of second-line pembrolizumab for the treatment of R/R cHL by the FDA in July 2020. The KEYNOTE-204 trial compared pembrolizumab with standard-of-care brentuximab vedotin in patients with R/R cHL.
Merck. FDA approves expanded indication for Merck’s KEYTRUDA® (pembrolizumab) in adult patients with relapsed or refractory classical Hodgkin lymphoma (cHL). https://www.merck.com/news/fda-approves-expanded-indication-for-mercks-keytruda-pembrolizumab-in-adult-patients-with-relapsed-or-refractory-classical-hodgkin-lymphoma-chl/. Published Oct 15, 2020. Accessed Oct 16, 2020.
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