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An expert panel hosted by
Customizing first-line BTK inhibitors for CLL
with Gilles Salles, Paolo Ghia, and Francesc Bosch
Wednesday, October 23, 2024
18:30-19:30 BST
This independent educational activity is supported by Pharmacyclics LLC, an AbbVie Company and Janssen Biotech. All content is developed independently by the faculty. The funder is allowed no influence on the content of this activity.
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During the 25th Congress of the European Hematology Association (EHA), the Lymphoma Hub spoke to Michael Dickinson, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, AU, about the phase I study of CD20-TCB (glofitamab) in relapsed/refractory non-Hodgkin lymphoma.
CD20-TCB is a novel T-cell-engaging bispecific antibody that has demonstrated high potency in the presence of other anti-CD20 antibodies. A phase I dose-escalation study (NCT03075696), evaluating the efficacy, safety, tolerability, and pharmacokinetic profile of CD20-TCB, is currently underway. Here, Michael Dickinson outlines the high response and complete remission rates observed amongst patients receiving active doses of CD20-TCB.
Phase I study of CD20-TCB, a novel T-cell-engaging bispecific antibody, in R/R NHL
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