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An expert panel hosted by
Customizing first-line BTK inhibitors for CLL
with Gilles Salles, Paolo Ghia, and Francesc Bosch
Wednesday, October 23, 2024
18:30-19:30 BST
This independent educational activity is supported by Pharmacyclics LLC, an AbbVie Company and Janssen Biotech. All content is developed independently by the faculty. The funder is allowed no influence on the content of this activity.
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The Lymphoma Hub is delighted to present a visual abstract summarizing key data from a phase II trial (NCT03075696) investigating the safety and efficacy of fixed-duration glofitamab monotherapy following pretreatment with obinutuzumab in adult patients with relapsed/refractory diffuse large B-cell lymphoma.
Glofitamab, a CD20 and CD3 bispecific monoclonal antibody that binds to CD20 b-cells and CD3 T-cells, leads to the engagement and redirection of a patient’s existing T-cells to eliminate malignant B-cells. Obinutuzumab is an anti-CD20 monoclonal antibody used in this study to mitigate cytokine release syndrome. The Lymphoma Hub has previously published an article and an interview on the phase I part of this study.
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